Axel Gremmelspacher studied at conservatoires in Freiburg, Boston and Hanover with Robert Levin, Raymond Santisi, James Avery and David Wilde as well as with John Perry in Toronto, having received a grant from the Rotary Foundation and the Canadian government. In 2001 he was awarded an Artist Diploma (Toronto) and in 2003 a solo diploma with honours (Freiburg). He also benefited greatly from master-classes with Leon Fleisher, André Laplante, Marc Durand, Wolfram Christ, Hansheinz Schneeberger, Jörg Widmann and Robert Aitken.
He has given many solo recitals and has appeared in various chamber music ensembles, especially with the violist Julia Rebekka Adler, the clarinettist Zoltán Kovács, the flautist Maiko lshiguro and as a member of the Trio Eusebius; he has been a frequent guest player with Ensemble Surplus. Axel Gremmelspacher teaches at the State Conservatory for Music Trossingen and at the Conservatory for Church Music of the Diocese of Rottenburg-Stuttgart.